This formula is so
powerful that it can be estimated how many minutes life will be extended
for each serving ingested. The biologic effects of this formula are so
profound that if it were widely used, actuarial survival for the entire
country could be expected to increase, with significantly greater
longevity, fewer and milder chronic diseases, and improved quality of
life for the population as a whole. Dr. Paul Frankel has estimated that
widespread use of this formula could save 50,000 lives per year in the
Testimonial: I took
Heartgems between 2007 and 2008, because of a serious recurrence of
heart symptoms, something that has affected me off and on since I
teenager. The symptoms gradually reduced over a period of about 3
till they were altogether gone, and my strength and resilience on
level had come back up. I would like to take them again now, as I am
having symptoms, but cannot currently afford to do so,
Hopefully that will change eventually.
Annie D 1/27/11
Testimonial: I love the
Heart Gems!!! I'm almost done with my first bottle and my fine motor
skills, my stammer, and my brain fog are much improved already. My
mood is also more stable, and my pH has been consistently higher.
Thank you so much for creating and distributing this product. I
want everyone I know and love to take it.
We are excited to announce the early results of our
major randomized prospective, double blind, placebo controlled, clinical
study, the first phase of which focused on the HeartGems formula
and its effects on blood chemistry and clinical symptoms. In the
following text are the dramatically positive results and their
The main marker we used for age reversing
effects on DNA is called homocysteine. Recent research indicates the
lower the homocysteine, the younger and healthier the condition of DNA.
Homocysteine elevation is also associated with increased cardiovascular
risks, with the risk rising exponentially above a level of 6.3, as the
following chart indicates:
Homocysteine Level <6.3 6.3 10 15
Relative Cardiac Risk <1 1 2 4
Thus at a level of 15, the risk of a major
cardiac event is 4 times that of the general population. Also a recent
study from Boston University indicates that a level over 14 carries
double the risk of Alzheimer’s disease. Noteworthy is that many labs
call a level up to 15 normal, resulting in what is likely widespread
under treatment of elevated levels.
In our double blind study 40 subjects above the age
of 40 were split randomly into treatment and placebo control groups.
The treatment group took increasing daily amounts of the HEARTGEMS
formula equivalent to 6, 12, and 18 capsules for one month each. The
placebo group only received capsules of maltodextrin.
Statistical analysis was done on the results to
derive scientific p values. A p value is the probability that a result
will occur by chance alone. For example, the p value for tossing a tail
in a coin flip is .5 or 50%. Values below .05 or 5% are felt to be
statistically significant. The lower the value, the greater the
significance of the results. A value of .001 is felt to be highly
significant, and anything at or below .0001 is very highly significant
for the difference between the treatment and control groups.
See Appendix A: Homocysteine
results for the treatment group at baseline, 1, 2, and 3 months are as
Baseline 1 month 2
months 3 months
7.1 6.8 6.1
.00001 .00001 .00001
The p values are treatment values compared to
baseline, which are all very highly significant. The entire group, on
average reduced to the lowest cardiac risk level.
See Appendix B: For the
placebo control group the values are as follows:
1 month 2 months 3 months
7.3 7.9 7.9
The abbreviation ns means not significant. There
was no significant change in control group levels throughout the course
of the study period.
See Appendix C: Even more
dramatic is the reduction in homocysteine for the treatment group
subjects that started with high homocysteine levels at or above 10.
1 month 2 months 3 months
9.3 8.3 7.3
This drop in homocysteine level is comparable to
the chemistry of persons in their 60’s becoming that of persons in their
20’s or 30’s. As each one-point drop in homocysteine may reduce cardiac
risks 10-12%, this suggests an up to 60-70% risk reduction for this
Subjects also took intensive symptom surveys that
compared them to the general population. The scores are in percentile
rank, the higher the percentile the greater the symptoms. A person at
the 60th percentile has more symptoms of that type than 60%
of the population.
See Appendix D: For the
anxiety scale, persons in the treatment group had the following results:
1 month 2 months 3 months
56 40 27
This indicates a very highly significant reduction
in anxiety scale for the treatment group. There was no significant
reduction in the placebo group.
Further preliminary analysis also suggests
significant reductions in somatization or body aches & pains (Appendix E), depression
(Appendix F), obsessive compulsive
(Appendix G), paranoid (Appendix H), hostility
(Appendix I), and global scales (Appendix J).
Appendix E: For Body Aches and Pains
Appendix F: For Depression
Appendix G: For Obsessive Compulsive
Appendix H: For Paroniod
Appendix I: For Hostility
Appendix J: For Global Severity
As the data analysis continues we will strive to
share more information as appropriate.
Based on these results, it can be strongly
recommended to take 3-6 HEARTGEMS daily for general health and
well-being. Persons with known elevated homocysteine levels may require
higher intake amounts for optimum results, best assessed with widely
available blood testing.
HEARTGEMS is an activated combination of the
most powerful nutrients ever studied for lowering harmful homocysteine
in the blood while increasing the production of the highly beneficial
Homocysteine is highly toxic to blood vessels and its level may be up
to 40 times more predictive of the risk of heart disease than the
cholesterol level. 44% of U.S. deaths are due to heart
disease. The average homocysteine level in the U.S. population is at an
unhealthy 10. Above the level of 7, every 3-point rise in homocysteine
increases heart attack risk by 35%.
Elevated homocysteine levels are
also strongly associated with the development of Alzheimer’s disease,
strokes, and increased complications in diabetes, lupus, and other
Homocysteine levels are increased with smoking,
alcohol overuse, oral contraceptive use, red meat ingestion, high fat
diets, and aging. One study showed that drinking 4 cups of coffee per
day elevates homocysteine levels by 10%.
The action of HEARTGEMS is driven by TMG
(trimethylglycine). See Figure A TMG provides methyl groups to detoxify
homocysteine. A methyl group consists of a carbon atom attached to
three hydrogen atoms. Methyl groups are widely used in the body for
detoxification and DNA repair. Choline also provides methyl groups, but
only in the liver and kidneys, and the ingredient inositol may also help
to lower homocysteine levels. Folic acid and vitamins B6 and B12 are
key cofactors required for homocysteine detoxification and independently
can reduce homocysteine levels. Zinc is another essential metabolic
cofactor for lowering homocysteine that is provided as a highly
absorbable and biologically active amino acid chelate.
almost all cases, adjusting the intake level of this formula to the
metabolic situation will be likely to lower homocysteine levels into the
lowest risk zone below 7. Significant homocysteine lowering typically
occurs within 1-3 months, which can be validated individually with a
homocysteine blood test. Using this formula, one patient with serious
heart disease showed a lowering of homocysteine level from 18 to 4 in
only 30 days, equating to an over 90% reduction in cardiac risk and
warranting long term life extending use.
In addition to reducing homocysteine levels, the
HEARTGEMS formula can also increase the beneficial internal
production of methionine, SAMe, DMG (dimethylglycine), glutathione, and
melatonin. For example, ingestion of the HEARTGEMS formula at
higher levels may increase SAMe by 400%. Some of the more significant
reported benefits of these internal HEARTGEMS byproducts are
summarized in the following table:
Methyl Group Donation (TMG, SAMe, and Choline)
May slow and even reverse
- Methyl groups break down harmful chemicals.
- Required for growth of new cells.
- Prevents DNA mutations and strand breaks.
- Prevents expression of disease causing genes.
- May reduce the risk of genetically induced
- Protects against alcohol induced liver injury.
- Increases serotonin levels and can be a potent
- Helps repair and preserve joint function.
- Potent relief of joint pain.
- Cell membrane stabilizer.
- Intimately involved in DNA protection and
- Enhances ATP, the fundamental cellular energy
- Well being promoter.
- Repairs liver injury.
- Protects the heart.
- Builds myelin sheaths around nerves.
- Maintains and repairs brain cells.
- Treats schizophrenia and dementia
- Supports nerve repair in demyelinating
diseases (like multiple sclerosis).
- May relieve symptoms in arthritis and Fibromyalgia.
- Promotes rejuvenative sleep.
- Immune enhancer.
- May reduce risk of cancer.
- One of the most powerful antioxidants ever
- Potent anti-cancer effects.
- Anti-aging actions.
- Increases physical energy.
- Enhances athletic performance.
- Improves function of autistic children.
- Reduces risk of heart attacks and stroke.
- Lowers risk of colon cancer.
- Decreases incidence of birth defects.
Lipotropic or Fat-directed Factors
(Methionine, Choline, and Inositol)
- Improves fluidity of cell membranes (required
for cell regeneration).
- Supports production and repair of myelin
sheaths of nerves.
- Detoxifies heavy metals and environmental
- Reduces toxic effects of cigarette smoke and
- Protects against injury from ionizing
- May enhance learning and memory.
- Improves metabolism of fat and cholesterol.
The HEARTGEMS components are
activated with a patented laser technology designed to energize the
methyl groups of trimethylglycine and promote their transfer.
A 1998 article in Medical Hypothesis presents evidence that aging may
be almost entirely due to a loss of methyl groups within the cells, with
elevated homocysteine a marker for impaired methyl group transfers
throughout the body. This study concludes that aging may be reversible
if aged cells could be stimulated to restore methyl group transfer
functions rather than losing them. HEARTGEMS provides all the
essential factors required for methyl group transfers.
The recommended use of HEARTGEMS is
one capsule three times daily with meals. For many persons, this level
of intake will reduce homocysteine levels to the lowest risk range.
Some persons may require 3-6 times this basic amount for optimum
results. This is especially true for persons with marked elevations of
homocysteine, or for persons with severe liver disease or genetic enzyme
abnormalities. Enhanced mood and increased physical energy are markers
that suggest adequate intake. Blood testing for homocysteine levels is
the most certain way to be sure the desired results have been achieved.
It is suggested that one capsule three
times per day be taken for the first month. After that, the use can be
increased to strive for desired levels of energy and mood enhancement,
relief of joint symptoms, or support of liver or brain nutrition. This
formula is a long-term rebuilder, restorer, and preventative, and
usually requires several weeks of use before the effects are perceived.
The components of the formula are very
safe. TMG has no side effects except for brief tension headaches if
large quantities are taken on an empty stomach. Choline may
occasionally deepen the depressive phase of manic-depressive illness.
Chronic intake of large amounts of vitamin B6, over 300-500mg per day,
may rarely cause nerve inflammation. Even at the highest suggested
intake of HEARTGEMS, this threshold for B6 would not be
exceeded. Although up to nine capsules three times per day may be
safely taken, clinical studies have not shown further benefit beyond the
levels of 6 capsules three times per day.
Persons who have taken this homocysteine
lowering combination of nutrients for 10 or more years report a marked
reduction in colds, increased energy and endurance, and reduced blood
sugar levels. Fat may melt off the body with ease with a return to more
youthful body proportions. Some people describe that this nutrient
blend makes them feel like young adults or even teenagers again.
Extended use of this formula is therefore
recommended to get the greatest possible individual benefits. Based
on cardiac risk factor reduction considerations alone, it is
estimated that with long term use each serving of HEARTGEMS may
extend life 15 minutes or more. HEARTGEMS may be the most powerful
life extending and enhancing formula ever offered.
is a breakdown of the benefits of HEARTGEMS by body system:
Reduction of total and LDL cholesterol, and total/HDL cholesterol
Rapid lowering of homocysteine levels, often reducing cardiac
risks > 50%.
Reduction and even reversal of lesions that narrow coronary
Provides essential elements to build insulating nerve coverings
Reduces risk of stroke and Alzheimer’s dementia
Supports production of serotonin, melatonin, and other
Protects the integrity of blood vessels throughout the body.
Lowers risk of peripheral vascular disease and gangrene.
May reduce the risks of vascular complications of diabetes.
Provides vital elements the liver uses to detoxify poisons.
May prevent or retard alcohol related liver injury and improve
May substantially reduce the risk of colon and liver cancer.
Has reversed pre-cancerous changes in bronchial lining cells to
Survival in operated lung cancer patients increased from 11 to 41
Helps protect the delicate air sacs of the lungs.
Reduces the risk of impotence.
May lower the risk of cervical cancer.
Helps metabolize and use sex hormones properly.
Lowers total body fat while helping to build muscle.
Improves metabolism of fat and cholesterol.
Clears toxins from the body.
May help repair immune cells in autoimmune diseases like lupus.
Helps to inactivate histamine in allergic responses.
Beneficial effects in immune cell tumor called lymphoma.
May reduce the tendency to osteoporosis.
Relieves the pain of arthritis and fibromyalgia.
Repairs and rebuilds the cartilage of joints.
Helps prevent DNA strand breaks and mutations.
Preserves the integrity of every cell line in the body.
May slow or stop telomere loss, retarding or reversing aging.
Restores the chemistry of DNA to a much younger biological age.
Loss of these nutrients greatly accelerates aging.
Research suggests human life extension of 7 to 17 years or more.
Mood and Energy
Generates internal production of SAMe, a powerful natural
Boosts serotonin to elevate mood – may act faster than
May significantly enhance energy, athletic performance, and
A Word on Heavy Metal Toxicities
some new, exciting news regarding our HeartGems product. The
product was being tested by a holistic dentist in Canada who, for the
past 4 years, has been seeking a product that can help his patients with
heavy metal toxicities. He does fecal elements tests to determine the
amount of toxins that are being excreted. He decided to test the
product on himself because he has no heavy metal toxicity (no more than
any of us do!) He likes to see what results he would get personally
before testing it on his patients. He went on the product for 6 days
taking 6 caps/day. He says it typically takes only 6 days if you are
going to see any difference at all. He was astounded with the results,
which were fantastic! The excretion of Mercury, Lead, Arsenic, Nickel,
& Tungsten were dramatically increased. Anywhere from 3 to 40 times as
much as before taking the HeartGems!! Very encouraging. He says
that in his past 4 years of searching he has never seen a product work
so well. He mentioned that many times other products he used would
dramatically increase the excretion of 1 metal but for reasons unknown
would actually DECREASE the excretion of others! HeartGems had
increases across the board with the exception of copper, which was the
only metal tested, that remained the same.
Doctor’s Data Lab Test Evaluation:
w/o amalgams Mercury 0.083
with amalgams Mercury 0.083
Take 1 capsule with each meal or as directed.
Advised against in persons with manic depressive illness or those
taking anti-depressants such as SSRIs, Tricyclics, or
MAO inhibitors because of the use of the ingredient Choline.
Trimethylglycine, Choline Bitartrate, Inositol-proprietary
blend of 1.62 g, Vitamin B3 (as insotal hexanicotinate) – 150mg, Vitamin
B6 (as pyridoxine hydrochloride-25mg and as pyridoxal-5-phosphate-5mg),
Vitamin B12 (as cyanocobalamin with dibasic calcium phosphate)-500mcg,
Folate (as folic acid)-800mcg Magnesium (from magnesium chelate)-15mg,
and Zinc (from Zinc chelate)-2.5mg. Also contains calcium chloride and
may contain silicon dioxide.
HeartGems 90 Capsules $36.77