5-Hydroxytryptophan (5HTP): Should not be taken by persons on monoamine oxidase inhibitor anti-depressants. Persons taking Serotonin Specific Reuptake Inhibitor (SSRI) anti-depressants like Prozac or Zoloft should consult with their health care practitioners before taking 5HTP supplements. Persons who have had sensitivity to 5HTP should avoid further use.